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M9630003.TXT
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1996-02-27
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Document 0003
DOCN M9630003
TI [Varicella-zoster virus pancreatitis in hematologic diseases]
DT 9603
AU Pulik M; Teillet F; Teillet-Thiebaud F; Lionnet F; Genet P; Petitdidier
C; Service d'Hematologie, Hopital Victor-Dupouy, Argenteuil
SO Ann Med Interne (Paris). 1995;146(5):292-4. Unique Identifier : AIDSLINE
MED/96099552
AB We report four cases of varicella-zoster pancreatitis in
immunocompromised hosts. All 4 patients presented a severe
immunodeficiency because of chronic lymphoproliferative disorders
(mainly lymphoma and Hodgkin disease) and long-term immunosuppressive
therapy. Varicella zoster pancreatitis is a very unusual presentation of
varicella-zoster infection. Few cases of pancreatitis occurring after
bone marrow transplantation have been reported. All 4 patients presented
with acute epigastric pain associated with transient elevation of serum
amylase. The vesicular rash followed the presenting symptoms of severe
abdominal pain by 8 days. This clinical presentation, occurring in
immunocompromised patients, defines a set of symptoms which should lead
the physician to suspect varicella-zoster pancreatitis, even in the
initial absence of the characteristic skin vesicular eruption. Early
institution of antiviral therapy seems mandatory.
DE Adult English Abstract Hematologic Diseases/*COMPLICATIONS Herpes
Zoster/*ETIOLOGY Human *Immunocompromised Host Male Middle Age
Pancreatitis/*ETIOLOGY/VIROLOGY Retrospective Studies JOURNAL ARTICLE
REVIEW REVIEW OF REPORTED CASES
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).